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Thompson,C.B.Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis.Proc.Natl.Acad.Sci.U.S.A

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An imbalance of the gut microbiota can lead to immune activation and inflammation, particularly through an increase in pro-inflammatory lipopolysaccharides (LPS), which results in increased production of inflammatory cytokines, such as TNF-, IL-1, and IL-6 (218)

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