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It is noteworthy that in the phentermine 15 mg/topiramate 92 mg arm of CONQUER, 192 of 995 participants in the total population discontinued due to adverse events (it was unclear how many of the 664 participants with T2DM in this arm discontinued), which was notably higher than the placebo and phentermine 7.5 mg/topiramate 46 mg treatment arms (89 of 994 and 58 of 498 discontinuations due to adverse events, respectively)

Managing side effects Side effect management is crucial for staying on treatment long enough to see results

Once disc material is removed, it does not regenerate

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For each line item on the bill, a model calculates a risk scorei.e., the likelihood of a billing anomaly based on provisions in the legal services agreement and adjustments in past data