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In the Rybelsus trials, gastrointestinal complaints rose with dose: for example, nausea was reported by about 6 percent of people on placebo, 11 percent on the 7 mg tablet, and 20 percent on the 14 mg tablet, and the majority of nausea, vomiting, and diarrhea occurred during dose escalation rather than steady state

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The average amount of time the subjects have been on ART is approximately 3.7 years