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Multi-country, multi-center long-term cardiovascular outcome trials (CVOTs) confirmed that GLP-1RAs decrease cardiovascular mortality and provide cardiovascular benefits to reduce the incidence of MI or non-fatal stroke [3]

Options include SGLT-2 inhibitors (which have no established pancreatitis signal), sulfonylureas, or insulin, depending on your overall glycemic and cardiovascular risk profile

It is associated with a heightened risk of developing type 2 diabetes and heart disease, and it can also affect bone health and reproductive functions

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