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6 However, unlike SGLT-2i, liraglutide did not significantly reduce the incidence of hospitalization for patients with heart failure, which was a predominant benefit with empagliflozin, 48 although the drug was associated with delayed cardiovascular benefits, possibly due to the modification of progression of atherosclerotic cardiovascular disease

Caffeine is replaced by vitamin B3, which supports energy metabolism and contributes to the reduction of tiredness and fatigue

In addition, ROS modifies the intracellular influx of calcium, resulting in interstitial oedema, haemoconcentration, and ischemia, as well as further production of ROS, creating a self-perpetuating cycle [47]

Practice Update January 27, 2017

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