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Using a panel of 13 ALL cell lines (6 B-cell precursors and 7 T-cell ALL precursors) and untargeted hydrogen nuclear magnetic resonance ( 1 H-NMR)-based metabolomics, we characterized MTX-triggered metabolic disturbance in detail

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Lack of drugdrug interaction was concluded if 90% confidence intervals (CIs) for the ratio of area under the plasma concentrationtime curve (AUC) or maximum concentration ( C max ), with/without oral semaglutide, were within a pre-specified interval (0.801.25)

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