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However, only in a minority of PCOS patients with overweight/obesity, a 510% weight loss goal is achieved with lifestyle intervention alone

This is by design

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Just don't take more than the serving size, as a two gummy serving already provides 125,000% of the daily value for B12

Repeat imaging at 612 months helps assess treatment response, with clinically meaningful improvement defined as at least a 30% relative reduction in hepatic fat content