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When confronted with harmful substances such as toxins or byproducts of oxidative stress in the periphery or brain tissue, the vascular system flexibly initiates defensive mechanisms to mitigate potential harm, demonstrating an adaptive response that protects the BBBs protective function

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The results showed that the intervention of multiple Lactobacillus species could restore the levels of alanine, arginine, aspartic acid, glycine and tryptophan in serum, and increase the contents of butyric acid, valeric acid, palmitic acid, palmitic acid, stearic acid and oleic acid

Notably, significant weight loss in the DZN-treated group was observed between the 10th and 11th weeks