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In general, the reductions in these serious outcomes were larger than those seen for new diagnoses, falling in the range of about 25% to 50%

The incidence of malformations exceeded concurrent and historical controls at 0.01 mg/kg/day (kidneys, scapula), 0.01 mg/kg/day (eyes, forelimb), 0.025 mg/kg/day (brain, tail and sacral vertebrae, major blood vessels and heart, umbilicus), 0.025 mg/kg/day (sternum) and at 0.05 mg/kg/day (parietal bones, major blood vessels)

For instance, intact cells and cell-free extracts of Bifidobacterium animalis 01 can scavenge hydroxyl radicals and superoxide anion in vitro , whereas in vivo , they increase the antioxidative enzyme activity (225, 226)