It is true that methylfolate and methylcobalamin work together synergistically along the methylation cycle pathway, but that doesnt necessarily mean that if you tolerate methylfolate well youll also need, want or tolerate methylcobalamin well (even if thats what most doctors, nutritionists, etc
Remember, everyone's body is different, so results may vary from person to person
Kurysheva, N
According to the National Academies of Sciences, Engineering, and Medicine (NAP), a safe highest level is called the tolerable upper intake level. Assessment of what amount is too much is based on animal and human studies, published evidence of adverse events, and professional agreement based on a committee of experts
It is marketed as a nasal spray (0.1% and 1% solutions) for the treatment of cognitive disorders, ischemic strokes, and optic nerve neuropathies