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Probiotic-rich foods such as yogurt, kefir, and fermented vegetables may support gut health, though evidence specific to GLP-1-induced constipation remains limited

As hexarelin binds to the CD36 receptors located on blood cells, it greatly improves cardiovascular functioning by maintaining normal cardiac parameters such as left ventricular ejection fraction (LVEF), cardiac output, and stroke volume, and decreasing the peripheral resistance in the blood vessels (2)

GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) improve blood glucose control and promote weight loss by mimicking a natural gut hormone

285,286 NAMPT inhibition in cancer has been associated with an increase of AMPK activity