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Key Takeaways Metformin can interfere with vitamin B12 absorption, leading to deficiency in up to 41% of long-term users

References Pfizer (Genotropin) Prescribing Information Adult GH deficiency dosing: recommended start 0.450.90 IU (0.150.30 mg) SC daily

Despite this, cyanocobalamin has been increasingly criticised in recent years, due to the following reasons: Toxicity: cyanocobalamin is often claimed to be toxic, as the cyano group form the poison cyanide

So, if for example you experience worse fatigue after B12 injections, it might be a brief phase where your body is still using the unhealthy red blood cells

Research on the relationship between vitamin B12 and cancer is still in its early stages, and science-backed findings remain inconclusive