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First, investigational is not a criticism of the data CagriSemas evidence is large-scale, randomized, and controlled but it does mean there is no approved indication, no approved dose, and no completed regulatory safety determination behind it yet

Some approximate equivalencies have emerged from clinical observation, though these should guide rather than dictate dosing decisions

Indeed, recent studies have found that over 10 distinct cell types likely reside in the nodose ganglion according to the expression profile of various proteins and receptors, but the results are sometimes contradictory 28,31,32

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