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The bile acid pool, estimated at 24 grams, circulates six to 10 dimes daily through the enterohepatic circulation

Optimizing in vivo delivery and genome editing methods, including the use of DSB-free large DNA knock-in technologies like PASTE and dCas9-SSAP editor, could help bridge the gap between pre-clinical development and clinical translation 41,42,43,44,45,46

Kim, MD President, Pennsylvania Pain Society

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