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The copper component contributes essential cofactor activity for enzymes involved in melanin synthesis and structural protein cross-linking, supporting both pigmentation and mechanical properties of hair fibers

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In 201718, the TGA conducted 243 post-marketing compliance reviews, of which 53 per cent were found to have had a compliance breach

However, the symptoms can vary significantly over time, and most patients can be managed effectively with physical therapy, anti-inflammatory medication, and epidural injections without ever needing surgery

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