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In addition, in the model of rapidly progressive RP, iron chelating agentsnamely, 5-(4-(2-hydroxyethyl) piperazin-1-yl (methyl)-8-hydroxy-quinoline) (VK28) and 5-(N-methyl-N-propargyaminomethyl)-quinoline-8-oldihydrochloride (VAR10303), preserve visual acuity and substantially rescue cones, indicating chelation of labile iron as a new method to treat RP (82)

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PMID: 41 HrmVKnuuttilaMVirtanenJMirttiTKohonenPKovanenPet al

In children with reflux disease, the severity of EE has been shown to correlate with the intensity of oxidative stress, with a linear relationship between tissue SOD levels and the De Meester score