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The brain response to natural GLP-1 stimulation is subtle compared to medications

Methods Animal studies Mice All animal experiments were approved by the Danish National Committee for Animal Studies, Ministry of Justice (2013-15-2934-00833), and were performed in accordance with EU Directive 2010/63/EU, Danish legislation governing animal experimentation (1987) and guidelines from the National Institutes of Health (publication number 85-23)

The response is highly individual and short-lived during and after meals

PMID: 7729267

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