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In the classical model, L cellderived GLP-1 is secreted in response to feeding and acts as an endocrine hormone to signal through the cell GLP-1R to potentiate GSIS (10)

Because AOD-9604 does not suppress appetite mechanisms in the first place, there is no adaptation of hunger-regulating neurons and no compensatory hunger amplification when the peptide is stopped

If you have specific health concerns, please consult your healthcare professional

Choosing foods that are easier to digest, such as well-cooked vegetables, lean proteins, and refined grains, can help minimize symptoms

PubMed McGowan JD, Altman RE, Kanto WP Jr