The primary pathway involves amplification of glucose-triggered insulin production by pancreatic beta cells, which enhances adipose tissue nutrient uptake and reduces circulating free fatty acid flux to the liver [28]
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FMT in animal models has been found to reduce the abundance of the Akkermansia genus (in phylum Verrucomicrobia) and increase the abundance of the Prevotella genus (in phylum Bacteroidetes) in gut microbiota (Tankou et al., 2018b), which is in line with findings of decreased gut Akkermansia after probiotic interventions and increased gut Prevotella after first-line disease-modifying treatments and time-restricted eating in MS patients (Jangi et al., 2016
The deletion of genes can affect protein synthesis