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5 , following studies analyzing the influence by treating together or alone with nitric oxide inhibitor, N -nitro-l-arginine methyl ester (L-NAME) or nitric oxide precursor, L-arginine all showed that the nitric oxide modulation is involved in the healing effect of BPC 157 in different tissue injuries

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Figure 4F illustrates that both targeting peptides significantly inhibited caspase-3 activity since decreasing fluorescence intensities of caspase-3 substrates were observed

doi: 10.3390/cells9102229 198 DevosDMoreauCDevedjianJCKluzaJPetraultMLalouxCet al