Exercise Mimetics and Future Peptide Therapies Compounds like SLU-PP-332 are currently being researched as exercise mimetics. These compounds activate estrogen-related receptors (ERRs) to mimic the physiological changes usually induced by endurance exercise, such as increased fatty acid oxidation and enhanced mitochondrial biogenesis
Compared to other antidiabetic medications, including metformin, sulfonylurea, thiazolidinediones (TZDs), dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT-2) inhibitors, and insulins, GLP-1-RAs boast a combination of high efficacy in glycemic control, desirable function of weight loss, low risk of hypoglycemia, and even a mild benefit on the cardiovascular system
Inflammation 48 , 223235 (2025)
Each mutant was confirmed by DNA sequencing