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With an average weight loss of 12.4% in trials, it offers flexibility for patients preferring a less restrictive regimen

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Keinesfalls sollte man die Dosierung der Tabletten selbststndig erhhen oder verringern: Das kann dazu fhren, dass die Tabletten nicht ausreichend wirken oder mehr Nebenwirkungen auslsen

BACKGROUND: Incretin-based therapies such as glucagon-like peptide-1 receptor agonists (GLP-1Ras), dual GLP-1/GIP agonists and amylin analogues have demonstrated significant weight loss benefits

Elafibranor (GFT505) Elafibranor is an unlicensed dual agonist of PPAR/ receptors, and has been shown to improve steatosis, inflammation, and fibrosis in mouse models of NAFLD [30]