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Energy stress-mediated AMPK activation and the activation of the Nrf2 antioxidant pathway also play important roles in regulating ferroptosis, through which metformin could alleviate ferroptosis and vascular calcification in high-lipid model mice

Galloway, D

One practical approach: researchers can begin with the GLOW formulation for initial tissue repair studies and transition to KLOW when the research design expands to include inflammatory pathway analysis