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Sialyl Tn or STn (Neu5Acα2-6GalNAcα-O-Ser) at Ser140 and Neu5Acα2-6GalNAcα-O-Thr at Thr139
/ β-Glc-PEG3-Azide / β-Glc-PEG3-N3
α-GalNAc-C4-COOCH3
9-trioxaundecyl) β-D-Maltobioside
C114H180N32O43S / 2718
PE936000: Galα(1-3)lactose-β-PEG3-NHCO-PEG10-Maleimide label-new Sialyl Tn or STn (Neu5Acα2-6GalNAcα-O-Ser)N A N A A Gal1 3lactose ( Gal epitope) ligand equipped with a maleimide through an NHCO PEG10 spacer. The maleimide reacts selectively with free thiols, such as cysteine residues, to form stable thioether conjugates. This compound presents a terminal Gal1 3 linkage corresponding to the Gal epitope (Gal1 3Gal1 4GlcNAc Gal1 3lactose), the target of abundant naturally occurring human anti Gal antibodies and central to xenotransplantation and anti Gal
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