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Using health data from over 2 million people, they looked at which health outcomes were associated with taking GLP-1s

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174,175 Acute liver injury induced by carbon tetrachloride leads to activation of the Wnt/-catenin signalling pathway, which manifests as an increase in the level of the Wnt target gene AXIN2

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The SELECT safety analysis found breast cancer rates were marginally lower on semaglutide than placebo, and a 2025 meta-analysis of 50 randomised GLP-1 trials found no increased breast cancer risk