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Histopathological evaluation demonstrated a reduced expression of inflammatory cytokines, such as IL-17, IL-23, and TNF, in the psoriatic skin of patients receiving liraglutide, suggesting a potential link to skin lesion improvement [148]

Weekly injections in this phase are important for: Keeping B12 stores full Watching how the patient responds and adjusting as needed Starting to move to less frequent injections Maintenance Phase: Monthly Injections After the first two phases, maintenance therapy starts with monthly injections

GENERAL ANNUAL DEDUCTIBLES AMONG ALL COVERED WORKERS As discussed above, the share of covered workers in plans with a general annual deductible has increased significantly over time, from 78% in 2013 to 90% in 2023 [Figure 7.7]

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