These symptoms are not typical issues to self-manage with an over-the-counter patch and may need urgent evaluation
doi: Hostynek JJ, Dreher F, Maibach HI
As can be seen from Volcano Figure 11 , the FI group up-regulated 31 differential metabolites and down-regulated 2 differential metabolites relative to the NC group

Committee I, Halperin J, Williams E, Fuster V, Task Force 1: Training in Ambulatory C, Fuster V, Halperin J, Williams E, Cho N, Iobst W, Mukherjee D, Vaishnava P, Medicine T, Smith S, Bittner V, Gaziano J, Giacomini J, Pack Q, Polk D, Stone N, Wang S, Task Force 3: Training in Electrocardiography A, Balady G, Bufalino V, Gulati M, Kuvin J, Mendes L, Schuller J, Imaging T, Narula J, Chandrashekhar Y, Dilsizian V, Garcia M, Kramer C, Malik S, Ryan T, Sen S, Wu J, Echocardiography T, Ryan T, Berlacher K, Lindner J, Mankad S, Rose G, Wang A, Cardiology T, Dilsizian V, Arrighi J, Cohen R, Miller T, Solomon A, Udelson J, Imaging T, Garcia M, Blankstein R, Budoff M, Dent J, Drachman D, Lesser J, Grover-McKay M, Schussler J, Voros S, Wann L, Imaging T, Kramer C, Hundley W, Kwong R, Martinez M, Raman S, Ward R, Medicine T, Creager M, Gornik H, Gray B, Hamburg N, Mohler E, White C, Catheterization T, King S, Babb J, Bates E, Crawford M, Dangas G, Voeltz M, Task Force 11: Training in Arrhythmia Diagnosis and Management C, Calkins H, Awtry E, Bunch T, Kaul S, Miller J, Tedrow U, Failure T, Jessup M, Ardehali R, Konstam M, Manno B, Mathier M, McPherson J, Sweitzer N, Cardiology T, OGara P, Adams J, Drazner M, Indik J, Kirtane A, Klarich K, Newby L, Scirica B, Sundt T, Disease T, Warnes C, Bhatt A, Daniels C, Gillam L, Stout K, Activity T, Harrington R, Barac A, Brush J, Hill J, Krumholz H , Lauer M, Sivaram C, Taubman M, Williams J

A Western diet is known to increase both glycogen and fat in the liver, and, as expected, both glycogen and liver fat (triglycerides) were markedly elevated in the WD+stevia group (Figure 3AC)