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Further information is available via The Bridges webpage for The Book of Knowledge.
de Wit HM, Vervoort GM, Jansen HJ, de Galan BE, Tack CJ
How This Works 5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small molecule that selectively inhibits Nicotinamide N-methyltransferase (NNMT)
Studies with single oral doses in normal subjects and with multiple oral doses in patients with Type 2 diabetes have shown significant absorption of glimepiride within 1 hour after administration and peak drug levels (Cmax) at 2 to 3 hours
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