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Blood pressure effects of sodium-glucose co-transport 2 (SGLT2) inhibitors

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Retatrutide markedly suppressed the expression of pro-inflammatory cytokines (TNF- , caspase-1, and NLRP3) and pro-fibrotic factors (fibronectin, -SMA, and collagen I) in treating diabetic kidney disease (DKD) in db/db mice (54)

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Birth defects occur in 3-4% of pregnancies among women with these conditions versus 2-3% in the general population

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