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[DOI] [PMC free article] [PubMed] [Google Scholar] 265.Niehues P., Wegner F.K., Wolfes J., Willy K., Ellermann C., Vollenberg R., Reinecke H., Rosenow F., Lepper J., Sackarnd J., et al

HO-1, an Nrf2-regulated antioxidant factor, catalyzes heme degradation and releases anti-inflammatory mediators, thereby exerting anti-inflammatory effects 15

Understanding this dose-response curve is key to efficient and effective protocol design