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GSTs, primarily GSTA1-1, are involved in the first step of the metabolic pathway of busulfan 79,80

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929 TRPM2 deficiency alleviates I/R-induced liver dysfunction and cell ferroptosis in mice, and ferroptosis induced by TRPM2 is related to the up-regulation of ALOX12 expression caused by mitochondrial Ca 2+ accumulation

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It is most concentrated in cortical glial cells and microgliakey immune cells accounting for 10% of brain cells