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Consistent with these mechanisms, increasing preclinical evidence demonstrates that natural products can synergize with immune checkpoint inhibitors (ICIs) to overcome therapeutic resistance

In conclusion, while herbal medicines hold significant promise for the treatment of GI disorders, their large-scale clinical acceptance depends on robust standardization protocols, adherence to national and international regulatory guidelines, and overcoming persistent challenges related to formulation stability, labeling, and quality assurance

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doi: 10.1210/js.2019-00078 [DOI] [PMC free article] [PubMed] [Google Scholar] 80

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