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The peptides influence on neurotransmitters such as 5-HT, glutamate, dopamine, and melatonin is assessed

The case report literature on GLP-1 agonists and anorgasmia identifies decreased norepinephrine signaling as a potential contributor to orgasmic dysfunction, which represents a separate but related concern from decreased desire

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Other Roles: Oxytocin may also be involved in sexual arousal, trust, and even social perception

There were relatively few direct comparative studies on animal models and human counterparts in terms of their nasal anatomy and physiology, and these studies would have been valuable in clarifying the specific similarities and differences between the two species