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The high acid load can irritate the gastric mucosa, trigger severe acid reflux, and cause osmotic diarrhea by drawing excess water into the bowel

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Kandel ER, Schwartz JH, Jessell TM (2000)

While these medications primarily reduce fat body mass (FBM), loss of lean body mass (LBM) can also occur, raising concerns about muscle loss in susceptible populations, such as frail individuals and older adults

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