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If you have not reacted adversely, you can now increase your application frequency to twice a day to enhance its efficacy

10.1007/BF03179215

It could be the fact that the hand or finger is not exposed to things out in the world

U100: 0.1 = 10 (1 = 100 ), 225 mcg: 225 2500 /1 = 0.09 = 9 263 mcg: 263 2500 /1 = 0.105 = 10.5 300 mcg: 300 2500 /1 = 0.120 = 12 338 mcg: 338 2500 /1 = 0.135 = 13.5 375 mcg: 375 2500 /1 = 0.150 = 15 413 mcg: 413 2500 /1 = 0.165 = 16.5 450 mcg: 450 2500 /1 = 0.180 = 18 488 mcg: 488 2500 /1 = 0.195 = 19.5 525 mcg: 525 2500 /1 = 0.210 = 21 563 mcg: 563 2500 /1 = 0.225 = 22.5

(2003) Randomized, placebo-controlled trial of intramuscular vitamin B12 for the treatment of hyperhomocysteinaemia in dialysis patients