Indeed, c-myc induces the transcription of glutamine transporters, such as SLC1A5/ASCT2, and also promotes the expression of glutamine-catabolized enzymes such as glutaminase 1 (GLS1) and carbamoyl-phosphate synthetase 2 - aspartate transcarbamylase - dihydroorotase (CAD), in order to encourage glutamine uptake by converting glutamine to glutamate [19-21]
The following guidance reflects current clinical recommendations and patient safety advice
Other possible side effects include facial flushing, headache, and a temporary increase in blood pressure
Bibcode:2000BBRC..272..416L
If replicated in a larger sample, the present finding of GSH deficit in women at risk of suicide may provide important information for the development of new paradigms of assessment, prevention, and treatment