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Photoproducts and metabolites of a common insect growth regulator produce developmental deformities in Xenopus

The MHRA-approved SmPC does not include hiccups (singultus) amongst the documented adverse reactions reported during clinical trials or post-marketing surveillance

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For long-term use in humans, implantable light probes must be operable and biocompatible as well as there must be efficient delivery, retainment, and expression of opsins in vivo to target cells with minimal adverse immune responses