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[91] demonstrated that impaired autophagy or unresolved ER stress in intestinal epithelial cells (IECs) led to increased activity of two upstream coactivators of ATF6: Acyl-CoA synthetase long-chain family member 1 (ACSL1) and casein kinase 2 Beta (CSNK2B)

Although the diagnosis and preventative strategy may be rather straightforward, much is unclear about the pathophysiology and heterogeneity of this inherited genetic condition that underlies the severity of neonatal hyperbilirubinemia

This slowing down links to getting older and certain health hiccups that come with it