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Dosing, timing, and potential interactions all need consideration

Non-Squamous NSCLC First-line Treatment of Metastatic Non-squamous NSCLC with Pembrolizumab and Platinum Chemotherapy The safety of pemetrexed, in combination with pembrolizumab and investigators choice of platinum (either carboplatin or cisplatin), was investigated in Study KEYNOTE-189, a multicenter, double-blind, randomized (2:1), active-controlled trial in patients with previously untreated, metastatic non-squamous NSCLC with no EGFR or ALK genomic tumor aberrations

Glutathione (GSH) functions primarily as a potent intracellular antioxidant, neutralizing free radicals and reactive oxygen species (ROS) through its sulfur-containing thiol group

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The optimal ratios between components for different applications have not been scientifically established through controlled studies