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833 Urease adopts a C3-symmetric trimer of trimers () architecture (Figure 39A), harboring a buried binuclear Ni 2 active site (Figure 39B) featuring a bridging carbamylated Lys (Figure 39C), with all metal ligands derived from the -subunit

Given the presumed short 5-Amino-1MQ half life , a single daily dose is often insufficient for maintaining stable levels

[An endogenous dithiol with antioxidant properties: alpha-lipoic acid, potential uses in cardiovascular diseases]

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