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All participants gave written informed consent before enrollment into the study

While it decreases ROS generation by enhancing antioxidant enzyme activity, DPQ has also been associated with detrimental effects, including increased DNA damage and apoptosis in cardiomyocytes 170

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Among the gene sets, genes with roles in GSH metabolism (KEGG_GLUTATHIONE_METABOLISM, p value, 0.032) were substantially downregulated in Fabry kidney organoids, indicating that the molecular functions were relatively deactivated

First, glutamate-cysteine ligase (GCL) links glutamate and cysteine to form -glutamyl cysteine (rate-limiting steps)