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Studies show that THC (4080 mg/kg) improves thermal and mechanical hyperalgesia, enhances motor nerve conduction velocity (MNCV), and restores sciatic functional index (SFI) in rodent models [145, 146]
Regulation of genes including NFKBIA, TP53, BCL2, Bruton tyrosine kinase (BTK), STAT3, CCND1, STAT1, and NFKB1 were observed by formononetin treatment (10 g/mL)
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