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Committee member Tod Durham, senior vice president of the Foundation for Fighting Blindness, said that I voted no primarily for low-quality evidence around efficacy, and noted that there are approved drugs for these uses

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Moreover, nucleus and mitochondria contain multiple substrates for caspase-3 [265], which can also provide insight into the non-essential contribution of caspase-3 to eryptosis, since there are no downstream targets of caspase-3 in erythrocytes due to organelle clearance