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Decreased vitamin B12 absorption due to altered gut microbiota Potential for megaloblastic anemia in prolonged use Increased risk of neuropathy and other neurological complications Dose and Duration Considerations The risk of B12 deficiency with metformin depends on the dose and how long you take it

The body's capacity to absorb B12 from food is naturally limited by intrinsic factor, a protein produced in the stomach that binds to B12 and facilitates its absorption in the small intestine

One essential vitamin during pregnancy is Vitamin B12

As a water-soluble vitamin, excess B12 is typically excreted in urine rather than accumulating to toxic levels

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