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Hereditary or acquired defects in the transport mechanisms are the major cause of LC deficiency, leading to pathologies such as cardiomyopathy and skeletal muscle myopathy

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In the decades since, researchers have repeatedly returned to it as an open question in neurochemistry, with one influential review aptly describing it as a "still unresolved riddle" (Kovalzon et al., 2006)

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Incapsula incident ID: 326000850028496836-10716261252470088