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Phentermine is chemically and pharmacologically related to the amphetamines and works as a sympathomimetic, increasing catecholamine signaling

And then they looked at who was also on hormone replacement therapy, and that was either oral or transdermal estradiol, not vaginal estradiol

That language only makes sense if the determination is genuinely clinical, not guaranteed

Despite supporting weight loss, GLP-1 therapy may lead to a loss in lean muscle mass from a decreased nutritional intake from a reduced appetite