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Lower NAD+ levels are also associated with repair enzymes like PARP1 and sirtuins becoming less effective, allowing DNA damage and cellular stress to accumulate[1]

Scarpulla et al., 2012

This means that individual experiences of improved pain symptoms could be due to other factors, such as increased physical activity or improved metabolic health, rather than the drug itself

For individuals who are overweight or obese, losing weight may improve sexual health in several important ways, though responses vary between individuals