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Response: As stated in the CY 2015 OPPS/ASC final rule with comment period (79 FR 66770 through 67034), under our C-APC policy, we designate a service described by a HCPCS code assigned to a C-APC as the primary service when the service is identified by OPPS status indicator J1. We use complexity adjustments to provide increased payment for certain ( comprehensive services

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For this reason, First-in-Human trials are not only a procedural milestone in drug development

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