491,493 A recent study suggests that Ni II -specific binding couples an allosteric network of residues at an interface between the DNA binding and metal binding domains (Figure 16B), which in turn, appears to result in an increase in protein rigidity, locking NikR in a DNA binding-active conformation
In turn, the mechanistic/mammalian target of rapamycin (mTOR) is a sensor of oxidative stress and regulator of T cell lineage specification (Chi 2012)
Free Radical Biology and Medicine , 41 402: S149S150, doi:10.1016/j.freeradbiomed.2006.10.015 Meat Science and Applications, ch
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