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The reduced amount of oxygen reaching the brain might be to blame for the thinking and reasoning problems

doi: 10.1074/jbc.M111218200 61 MaatoukDMNatarajanAShibataYSongLCrawfordGEOhlerUet al

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No Observed Effects On: Blood glucose or insulin sensitivity (no diabetogenic effects) IGF-1 levels (remained within normal ranges) Blood pressure or cardiovascular parameters Thyroid function Liver or kidney function markers Important: The absence of growth hormone-related side effects distinguishes AOD-9604 from full-length GH, which can cause fluid retention, joint pain, carpal tunnel syndrome, and insulin resistance

Tirzepatide can be discontinued abruptly without a taper